Concepts inParameter synthesis for polynomial biological models
Polynomial
In mathematics, a polynomial is an expression of finite length constructed from variables and constants, using only the operations of addition, subtraction, multiplication, and non-negative integer exponents. For example, x ¿ x/4 + 7 is a polynomial, but x ¿ 4/x + 7x is not, because its second term involves division by the variable x (4/x), and also because its third term contains an exponent that is not an integer (3/2).
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Organic synthesis
Organic synthesis is a special branch of chemical synthesis and is concerned with the construction of organic compounds via organic reactions. Organic molecules can often contain a higher level of complexity compared to purely inorganic compounds, so the synthesis of organic compounds has developed into one of the most important branches of organic chemistry. There are two main areas of research fields within the general area of organic synthesis: total synthesis and methodology.
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Linear programming
Linear programming (LP, or linear optimization) is a mathematical method for determining a way to achieve the best outcome (such as maximum profit or lowest cost) in a given mathematical model for some list of requirements represented as linear relationships. Linear programming is a specific case of mathematical programming. More formally, linear programming is a technique for the optimization of a linear objective function, subject to linear equality and linear inequality constraints.
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Dynamical system
A dynamical system is a concept in mathematics where a fixed rule describes the time dependence of a point in a geometrical space. Examples include the mathematical models that describe the swinging of a clock pendulum, the flow of water in a pipe, and the number of fish each springtime in a lake. At any given time a dynamical system has a state given by a set of real numbers that can be represented by a point in an appropriate state space.
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Bernstein polynomial
In the mathematical field of numerical analysis, a Bernstein polynomial, named after Sergei Natanovich Bernstein, is a polynomial in the Bernstein form, that is a linear combination of Bernstein basis polynomials. A numerically stable way to evaluate polynomials in Bernstein form is de Casteljau's algorithm. Polynomials in Bernstein form were first used by Bernstein in a constructive proof for the Stone¿Weierstrass approximation theorem.
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