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Result 1 – 20 of 2,864
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1 published by ACM
July 2010 GECCO '10: Proceedings of the 12th annual conference companion on Genetic and evolutionary computation
Publisher: ACM
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 2,   Downloads (12 Months): 30,   Downloads (Overall): 166

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Keywords: bioinformatics, computational biology
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2 published by ACM
February 2016 SIGCSE '16: Proceedings of the 47th ACM Technical Symposium on Computing Science Education
Publisher: ACM
Bibliometrics:
Citation Count: 0

An ultimate goal of traditional textual criticism is the reconstruction of the archetype of a given work. By comparing differences and similarities among multiple versions of the work, the interrelations among existing and hypothetical ancestral versions can be naturally presented as a tree, in which a branch represents derivation of ...
Keywords: stemmatics, phylogenetics, computational biology
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3 published by ACM
August 2000 ACM SIGBIO Newsletter: Volume 20 Issue 2, Aug. 2000
Publisher: ACM
Bibliometrics:
Citation Count: 11
Downloads (6 Weeks): 2,   Downloads (12 Months): 53,   Downloads (Overall): 896

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The Biopython project was formed in August 1999 as a collaboration to collect and produce open source bioinformatics tools written in Python, an object-oriented scripting language. It is modeled on the highly successful Bioperl project, but has the goal of making libraries available for people doing computations in Python. The ...
Keywords: Python, bioinformatics, computational biology
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4
July 2009 IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB): Volume 6 Issue 3, July 2009
Publisher: IEEE Computer Society Press
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 0,   Downloads (12 Months): 3,   Downloads (Overall): 120

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Some genetic diseases in human beings are dominated by short sequences repeated consecutively called tandem repeats. Once a region containing tandem repeats is found, it is of great interest to study the history of creating the repeats. The computational problem of reconstructing the duplication history of tandem repeats has been ...
Keywords: Computational biology, approximation algorithms.
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5 published by ACM
January 1999 Journal of the ACM (JACM): Volume 46 Issue 1, Jan. 1999
Publisher: ACM
Bibliometrics:
Citation Count: 130
Downloads (6 Weeks): 10,   Downloads (12 Months): 69,   Downloads (Overall): 1,671

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Genomes frequently evolve by reversals &rgr;( i,j ) that transform a gene order &pgr; 1 … &pgr; i &pgr; i +1 … &pgr; j -1 &pgr; j … &pgr; n into &pgr; 1 … &pgr; i &pgr; j -1 … &pgr; i +1 &pgr; j … &pgr; n . Reversal ...
Keywords: computational biology, genetics
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6 published by ACM
August 2011 BCB '11: Proceedings of the 2nd ACM Conference on Bioinformatics, Computational Biology and Biomedicine
Publisher: ACM
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 4,   Downloads (12 Months): 9,   Downloads (Overall): 74

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With the increase of the number of available prokaryotic genomes, studies focusing on the higher level evolutionary events, including the evolution of whole genomes, are now possible. Simulated datasets are essential components in both the development and evaluation stages for all evolutionary studies. In this paper, we implemented the first ...
Keywords: evolution, bioinformatics, computational biology, genomics, simulation
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7 published by ACM
March 2004 ACM SIGCSE Bulletin: Volume 36 Issue 1, March 2004
Publisher: ACM
Bibliometrics:
Citation Count: 2
Downloads (6 Weeks): 1,   Downloads (12 Months): 9,   Downloads (Overall): 407

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Keywords: interdisciplinary education, bioinformatics, computational biology, genomics
Also published in:
March 2004  SIGCSE '04: Proceedings of the 35th SIGCSE technical symposium on Computer science education
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8
October 2008 IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB): Volume 5 Issue 4, October 2008
Publisher: IEEE Computer Society Press
Bibliometrics:
Citation Count: 6
Downloads (6 Weeks): 1,   Downloads (12 Months): 2,   Downloads (Overall): 100

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The gene-duplication problem is to infer a species supertree from gene trees that are confounded by complex histories of gene duplications. This problem is NP-hard and thus requires efficient and effective heuristics. Existing heuristics perform a stepwise search of the tree space, where each step is guided by an exact ...
Keywords: Algorithms, Phylogenetics, Computational Biology, Gene Duplication, Supertrees
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9 published by ACM
April 2014 HSCC '14: Proceedings of the 17th international conference on Hybrid systems: computation and control
Publisher: ACM
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 4,   Downloads (12 Months): 15,   Downloads (Overall): 78

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Real-time control has been recently applied to drive actual intracellular processes with unprecedented accuracy. Here we introduce the motivations for the development of these approaches and then present a platform for the real-time control of gene expression in yeast cells. We conclude by surveying related works and discussing possible future ...
Keywords: yeast, computational biology, gene expression, systems biology, synthetic biology
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10 published by ACM
September 2015 BCB '15: Proceedings of the 6th ACM Conference on Bioinformatics, Computational Biology and Health Informatics
Publisher: ACM
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 8,   Downloads (12 Months): 24,   Downloads (Overall): 57

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Background. Next Generation Sequencing (NGS) data has been extensively exploited in the last decade to analyse genome variations and to understand the role of genome variations in complex diseases. Copy number variations (CNVs) are genomic structural variants estimated to account for about 1.2% of the total variation in humans. CNVs ...
Keywords: computational biology, copy number variation, next generation sequencing
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11 published by ACM
May 2011 ICS '11: Proceedings of the international conference on Supercomputing
Publisher: ACM
Bibliometrics:
Citation Count: 1
Downloads (6 Weeks): 2,   Downloads (12 Months): 18,   Downloads (Overall): 148

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Interactions among proteins are essential to many biological functions in living cells but experimentally detected interactions represent only a small fraction of the real interaction network. Computational protein interaction prediction methods have become important to augment the experimental methods; in particular sequence based prediction methods that do not require additional ...
Keywords: high throughput, protein interaction prediction, computational biology, massively parallel application
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12 published by ACM
April 2003 RECOMB '03: Proceedings of the seventh annual international conference on Research in computational molecular biology
Publisher: ACM
Bibliometrics:
Citation Count: 4
Downloads (6 Weeks): 1,   Downloads (12 Months): 1,   Downloads (Overall): 875

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In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae . Genome-wide comparative analysis allowed the identification of functionally important sequences, both coding and non-coding. In this companion paper we describe the mathematical ...
Keywords: comparative genomics, computational biology, genome annotation, regulatory motif discovery
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13 published by ACM
March 2008 ACM SIGMETRICS Performance Evaluation Review: Volume 35 Issue 4, March 2008
Publisher: ACM
Bibliometrics:
Citation Count: 11
Downloads (6 Weeks): 1,   Downloads (12 Months): 5,   Downloads (Overall): 354

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We introduce a scalable framework built upon the BlenX language and inspired by the Beta-binders process calculus to model, simulate and analyse biological systems. We show the features of the Beta Workbench framework on a running example based on the mitogen-activated kinase pathway. We also discuss an incremental modelling process ...
Keywords: process calculi, computational biology, systems biology, modelling and simulation
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14
May 2014 IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB): Volume 11 Issue 3, May/June 2014
Publisher: IEEE Computer Society Press
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 1,   Downloads (12 Months): 4,   Downloads (Overall): 21

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Information theory has been used for quite some time in the area of computational biology. In this paper we present a pattern discovery method, named Fast Entropic Profiler, that is based on a local entropy function that captures the importance of a region with respect to the whole genome. The ...
Keywords: local entropy, computational biology, information theory, pattern discovery
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15 published by ACM
March 2002 SAC '02: Proceedings of the 2002 ACM symposium on Applied computing
Publisher: ACM
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 1,   Downloads (12 Months): 1,   Downloads (Overall): 126

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This paper describes ongoing work on a project to simulate the behaviour of epidermal growth factor receptors. These are structures which can be found on the surface of cells in the body, which receive and process chemical signals concerned with cell growth. We describe the implementation of a program which ...
Keywords: receptor biology, computational biology, individual-based models, modelling, simulation
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16 published by ACM
April 2001 RECOMB '01: Proceedings of the fifth annual international conference on Computational biology
Publisher: ACM
Bibliometrics:
Citation Count: 6
Downloads (6 Weeks): 0,   Downloads (12 Months): 6,   Downloads (Overall): 312

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The problem of fast searching of a pattern that contains Classes of characters and Bounded size Gaps (CBG) in a text has a wide range of applications, among which a very important one is protein pattern matching (for instance, one PROSITE protein site is associated with the CBG [ RK ...
Keywords: PROSITE, information retrieval, bit-parallelism, computational biology, pattern matching
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17 published by ACM
January 1997 RECOMB '97: Proceedings of the first annual international conference on Computational molecular biology
Publisher: ACM
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 2,   Downloads (12 Months): 2,   Downloads (Overall): 362

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Keywords: approximation algorithm, computational biology, evolutionary tree, multiple sequence alignment, phylogeny
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18 published by ACM
July 2012 GECCO '12: Proceedings of the 14th annual conference on Genetic and evolutionary computation
Publisher: ACM
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 2,   Downloads (12 Months): 9,   Downloads (Overall): 103

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While development plays a critical role in the emergence of diversity, its mechanical and chemical actions are considered to be inextricably correlated with genetic control . Since in most extant species the complex growth from zygote to adult organism is orchestrated by a complex gene regulatory network (GRN), the prevalent ...
Keywords: evolutionary development, morphogenesis, computational biology, tensegrity, indirect encoding
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19 published by ACM
April 2001 RECOMB '01: Proceedings of the fifth annual international conference on Computational biology
Publisher: ACM
Bibliometrics:
Citation Count: 2
Downloads (6 Weeks): 2,   Downloads (12 Months): 6,   Downloads (Overall): 516

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One of the key open problems in large-scale DNA sequence assembly is the correct reconstruction of sequences that contain repeats. A long repeat can confound a sequence assembler into falsely overlaying fragments that sample its copies, effectively compressing out the repeat in the reconstructed sequence. We call the task of ...
Keywords: disambiguating repeats, k-median problem, computational biology, shotgun sequencing
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20
January 2016 IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB): Volume 13 Issue 1, January/February 2016
Publisher: IEEE Computer Society Press
Bibliometrics:
Citation Count: 0
Downloads (6 Weeks): 4,   Downloads (12 Months): 20,   Downloads (Overall): 21

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Finding approximately conserved sequences, called motifs, across multiple DNA or protein sequences is an important problem in computational biology. In this paper, we consider the ( l, d ) motif search problem of identifying one or more motifs of length l present in at least q of the n given ...
Keywords: graph algorithms, hardware acceleration, finite automaton, computational biology, motif detection
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Result 1 – 20 of 2,864
Result page: 1 2 3 4 5 6 7 8 9 10 >>



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